GI 254023X
CAS No. | 260264-93-5 | Cat. No. | BCP25918 |
Name | GI 254023X | ||
Synonyms | GI254023X; GI-254023X;GI4023; GI-4023; GI 4023; SRI028594; | ||
Formula | C21H33N3O4 | M. Wt | 391.51 |
Description | GI254023X is a potent and selective ADAM10 Inhibitor with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis of H929 cells. Its mechanism may be associated with inbihition of Notch1 activation. | ||
Pathways | Protease/Metabolic Enzyme | ||
Targets | MMP |
Structure
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