GI 254023X

  • Chemical Properties
CAS No. 260264-93-5 Cat. No. BCP25918
Name GI 254023X
Synonyms GI254023X; GI-254023X;GI4023; GI-4023; GI 4023; SRI028594;
Formula C21H33N3O4 M. Wt 391.51
  • Biological Activity
Description GI254023X is a potent and selective ADAM10 Inhibitor with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis of H929 cells. Its mechanism may be associated with inbihition of Notch1 activation.
Pathways Protease/Metabolic Enzyme 
Targets MMP 

Structure

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