ALKS-8700

CAS No.	1577222-14-0	Cat. No.	BCP20867
Name	ALKS-8700
Synonyms	Diroximel fumarate; ALKS8700; ALKS 8700;
Formula	C11H13NO6	M. Wt	255.22

Description	Diroximel fumarate, also known as ALKS-8700, is in Phase III clinical trials for the treatment of relapsing remitting multiple sclerosis, which is the most common form of multiple sclerosis (MS). Relapsing remitting MS is characterized by episodes of worsening neurologic functioning followed by partial or complete recovery periods free of disease progression.Orally administered twice daily, diroximel fumarate is a prodrug of monomethyl fumarate (MMF) in a controlled-release formulation. A prodrug is a medication that, following administration, is converted into a pharmacologically active drug in the body. MMF has immunomodulating and neuroprotective effects.
Pathways	NFκB
Targets	NF κB

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