CPI-444
| CAS No. | 1202402-40-1 | Cat. No. | BCP20881 |
| Name | CPI-444 | ||
| Synonyms | CPI 444; CPI444; V81444; V-81444; V 81444; Ciforadenant; | ||
| Formula | C20H21N7O3 | M. Wt | 407.43 |
| Description | CPI-444, also known as V81444, is an orally administered antagonist of the adenosine A2A receptor. Upon oral administration, CPI-444 binds to adenosine A2A receptors expressed on the surface of immune cells, including T-lymphocytes, natural killer (NK) cells, macrophages and dendritic cells (DCs). This prevents tumor-released adenosine from interacting with the A2A receptors on these key immune surveillance cells, thereby abrogating adenosine-induced immunosuppression in the tumor microenvironment. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Adenosine Receptor | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.