Tropifexor
| CAS号 | 1383816-29-2 | 货号 | BCP20878 |
| 中文名 | Tropifexor | ||
| 英文名 | Tropifexor | ||
| 中文别名 | |||
| 英文别名 | LJN452; LJN-452; LJN 452; | ||
| 分子式 | C29H25F4N3O5S | 分子量 | 603.58 |
| 生物活性 | Tropifexor, also known as LJN452, is a farnesoid X receptor agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH). Potent in vivo activity was demonstrated in rodent PD models by measuring the induction of FXR target genes in various tissues. Tropifexor has advanced into phase 2 human clinical trials in patients with NASH and PBC. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | FXR | ||
结构式
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