Verubecestat TFA salt
CAS号 | 2095432-65-6 | 货号 | BCP26034 |
中文名 | Verubecestat TFA salt | ||
英文名 | Verubecestat TFA salt | ||
中文别名 | |||
英文别名 | Verubecestat TFA; MK 8931 TFA salt; MK8931 TFA salt; MK-8931 TFA salt;MK-8931; MK 8931; MK8931; MK-8931-009; SCH 900931; SCH-900931; SCH900931; | ||
分子式 | C17H17F2N5O3S.C2HF3O2 | 分子量 | 523.44 |
生物活性 | Verubecestat, also known as MK-8931 or SCH 900931, is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Verubecestat is a promising novel therapeutic drug candidate in Alzheimer's disease. Verubecestat reduced Aβ cerebral spinal fluids (CSF) levels up to 92% and was well tolerated by patients. | ||
信号通路 | Neuro Signaling Pathway | ||
靶 点 | Beta secretase |
结构式
![](https://img.biochemsafebuy.com/uploads/company8/20180110/1515561308_hxxyt.png)
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