GLPG1690

  • Chemical Properties
CAS No. 1628260-79-6 Cat. No. BCP20895
Name GLPG1690
Synonyms GLPG-1690;GLPG 1690;
Formula C30H33FN8O2S M. Wt 588.7
  • Biological Activity
Description GLPG1690 is a selective autotaxin inhibitor discovered by Galapagos, with potential application in idiopathic pulmonary disease (IPF). In a Phase 1 study in healthy human volunteers, GLPG1690 demonstrated favorable safety and tolerability, as well as a strong pharmacodynamic signal implying target engagement.
Pathways Protease/Metabolic Enzyme 
Targets Phosphodiesterase/PDE 

Structure

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