Valbenazine Tosylate

  • Chemical Properties
CAS No. 1639208-54-0 Cat. No. BCP26049
Name Valbenazine Tosylate
Synonyms NBI-98854; NBI 98854; NBI98854; MT-5199; MT 5199; MT5199;
Formula C38H54N2O10S2 M. Wt 762.97
  • Biological Activity
Description Valbenazine, also known as NBI-98854 and MT-5199, is a potent and selective VMAT2 inhibitor. NBI-98854 is effective in regulating the levels of dopamine release during nerve communication, while at the same time having minimal impact on the other monoamines. NBI-98854 is promising agent for the treatment of tardive dyskinesia.NBI-98854 significantly improved tardive dyskinesia and was well tolerated in patients. These results support the phase 3 clinical trials of NBI-98854 now underway.
Pathways Ion Channel/Membrane Transporter 
Targets Monoamine Transporter 

Structure

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