PTC-028
CAS No. | 1782970-28-8 | Cat. No. | BCP20909 |
Name | PTC-028 | ||
Synonyms | PTC 028;PTC028; | ||
Formula | C19H12F5N5 | M. Wt | 405.332 |
Description | PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification. In vivo, orally administered PTC-028, as a single agent, exhibits significant antitumor activity comparable with the standard cisplatin/paclitaxel therapy in an orthotopic mouse model of ovarian cancer. | ||
Pathways | Apoptosis Pathway Others Pathway Wnt/Stem Cell | ||
Targets | Apoptosis Inducer Autophagy BMI1 |
Structure
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