PTC-028

  • Chemical Properties
CAS No. 1782970-28-8 Cat. No. BCP20909
Name PTC-028
Synonyms PTC 028;PTC028;
Formula C19H12F5N5 M. Wt 405.332
  • Biological Activity
Description PTC-028 is an orally bioavailable compound that decreases BMI-1 levels by posttranslational modification. In vivo, orally administered PTC-028, as a single agent, exhibits significant antitumor activity comparable with the standard cisplatin/paclitaxel therapy in an orthotopic mouse model of ovarian cancer.
Pathways Apoptosis Pathway Others Pathway Wnt/Stem Cell 
Targets Apoptosis Inducer Autophagy BMI1 

Structure

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