Bictegravir Sodium
CAS No. | 1807988-02-8 | Cat. No. | BCP20910 |
Name | Bictegravir Sodium | ||
Synonyms | GS-9883; GS 9883; GS9883; GS-9883-01; GS9883-01; GS 9883-01; | ||
Formula | C21H17F3N3NaO5 | M. Wt | 471.36 |
Description | Bictegravir, also known as GS-9883, is a potent, unboosted, once-Daily HIV-1 Integrase Strand Transfer Inhibitor (INSTI) (IC50 - 1.6 nM) with improved pharmacokinetics and in vitro resistance profile. Bictegravir is currently in Phase 3 trials as part of a single tablet regimen in combination with tenofovir alafenamide (TAF) and emtricitabine (FTC) for the treatment of HIV-1 infection (bictegravir 50 mg/emtricitabine 200 mg/tenofovir alafenamide 25 mg). | ||
Related Products | 1611493-60-7(Bictegravir) | ||
Pathways | Protease/Metabolic Enzyme Microbiology/Virology | ||
Targets | Integrase HIV |
Structure
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