Diazoxide

CAS No.	364-98-7	Cat. No.	BCP26107
Name	Diazoxide
Synonyms	Eudemine; Hyperstat; Proglycem; Hypertonalum; Proglicem;
Formula	C8H7ClN2O2S	M. Wt	230.67

Description	Diazoxide is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels, preventing calcium flux across the sarcolemma and activation of the contractile apparatus. This agent also inhibits insulin release by interacting with ATP-sensitive potassium channels of pancreatic islet beta-cells.
Pathways	Ion Channel/Membrane Transporter
Targets	Potassium Channel

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