Rosiptor

  • Chemical Properties
CAS No. 782487-28-9 Cat. No. BCP26168
Name Rosiptor
Synonyms AQX-1125; AQX 1125; AQX1125;
Formula C20H35NO2 M. Wt 321.51
  • Biological Activity
Description Rosiptor, also known as AQX-1125, is an activator of SHIP1, which controls the PI3K cellular signaling pathway. If the PI3K pathway is overactive, immune cells can produce an abundance of pro-inflammatory signaling molecules and migrate to and concentrate in tissues, resulting in excessive or chronic inflammation. SHIP1 is predominantly expressed in cells derived from bone marrow tissues, which are mainly immune cells. Therefore drugs that activate SHIP1 can reduce the function and migration of immune cells and have an anti-inflammatory effect. By controlling the PI3K pathway, Rosiptor reduces immune cell function and migration by targeting a mechanism that has evolved in nature to maintain homeostasis of the immune system.
Related Products 782487-29-0(Rosiptor acetate)
Pathways Protease/Metabolic Enzyme 
Targets Phosphatase 

Structure

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