Prima-1

CAS No.	5608-24-2	Cat. No.	BCP26191
Name	Prima-1
Synonyms	2,2-Bis(Hydroxymethyl)-3-Quinuclidinone; 2,2-Dimethylolquinuclidin-3-One;
Formula	C9H15NO3	M. Wt	185.22

Description	PRIMA-1, named for p53 reactivation and induction of massive apoptosis, is an inhibitor of the growth of cell lines derived from various human tumor types in a mutant p53-dependent manner. PRIMA-1 restores sequence-specific DNA binding and transactivational activity to mutant p53 proteins at relatively high µM to mM concentrations. It is therefore a unique anti-oncogenic substance, working as a re-activator of the apoptotic function of mutant p53 via conformational modulation of function-specific epitopes.
Pathways	Apoptosis Pathway Others Pathway
Targets	Autophagy p53

Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.

For product details of different batches, please contact our Customer

Products are for research use only and not for human use. We do not sell to patients.