Secukinumab
CAS No. | 875356-43-7/1229022-83-6 | Cat. No. | BCP26257 |
Name | Secukinumab | ||
Synonyms | AIN457;AIN 457;AIN-457; | ||
Formula | C6584H10134N1754O2042S44 | M. Wt | 147.94 kg/mol |
Description | Secukinumab inhibits a member of the cytokine family, interleukin 17A, which is produced mainly by inflammatory T helper 17 cells.IL17A is upregulated in serum of people with psoriasis and in the synovial fluid of people with psoriatic arthritis, and promotes inflammation when it binds to the interleukin-17 receptor which is expressed in various types of cells, including keratinocytes in skin. | ||
Pathways | Others Pathway | ||
Targets | Interleukin Related |
Structure
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