苏金单抗
| CAS号 | 875356-43-7/1229022-83-6 | 货号 | BCP26257 |
| 中文名 | 苏金单抗 | ||
| 英文名 | Secukinumab | ||
| 中文别名 | |||
| 英文别名 | AIN457；AIN 457；AIN-457; | ||
| 分子式 | C6584H10134N1754O2042S44 | 分子量 | 147.94 kg/mol |
| 生物活性 | Secukinumab inhibits a member of the cytokine family, interleukin 17A, which is produced mainly by inflammatory T helper 17 cells.IL17A is upregulated in serum of people with psoriasis and in the synovial fluid of people with psoriatic arthritis, and promotes inflammation when it binds to the interleukin-17 receptor which is expressed in various types of cells, including keratinocytes in skin. | ||
| 信号通路 | Others Pathway | ||
| 靶 点 | Interleukin Related | ||
结构式
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