CC-90003
| CAS No. | 1621999-82-3 | Cat. No. | BCP23624 |
| Name | CC-90003 | ||
| Synonyms | CC 90003; CC90003; | ||
| Formula | C22H21F3N6O2 | M. Wt | 458.44 |
| Description | CC-90003 is an orally available inhibitor of extracellular signal-regulated kinase (ERK), with potential antineoplastic activity. Upon oral administration, CC-90003 inhibits ERK activity, and prevents the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival. | ||
| Pathways | MAPK Pathway | ||
| Targets | MEK/ERK | ||
Structure
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