AZD5069
| CAS No. | 878385-84-3 | Cat. No. | BCP23519 |
| Name | AZD5069 | ||
| Synonyms | AZD-5069; AZD 5069; | ||
| Formula | C18H22F2N4O5S2 | M. Wt | 476.52 |
| Description | AZD-5069 is a potent and selective CXCR2 antagonist used for caner treatment. AZD-5069 was shown to inhibit binding of radiolabeled CXCL8 to human CXCR2 with a pIC50 value of 9.1. Furthermore, AZD5069 inhibited neutrophil chemotaxis, with a pA2 of approximately 9.6, and adhesion molecule expression, with a pA2 of 6.9, in response to CXCL1. AZD5069 was a slowly reversible antagonist of CXCR2 with effects of time and temperature evident on the pharmacology and binding kinetics. AZD-5069 is also potential useful for patient in inflammatory conditions. | ||
| Pathways | GPCR/G Protein | ||
| Targets | CXCR | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.