APS279 hydrochloride
| CAS No. | 2002381-31-7 | Cat. No. | BCP23567 |
| Name | APS279 hydrochloride | ||
| Synonyms | APS-2-79 HCl;APS279 HCl;APS 2-79 HCl; | ||
| Formula | C23H22ClN3O3 | M. Wt | 423.89 |
| Description | APS-2-79 is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK. IC50=120 ± 23 nM. | ||
| Pathways | MAPK Pathway | ||
| Targets | MEK/ERK | ||
Structure
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