Octreotide

  • Chemical Properties
CAS No. 83150-76-9 Cat. No. BCP28870
Name Octreotide
Synonyms Octreotide acetate; Longastatin; SMS-201-995; Octreotide-LAR; SMS 201-995;
Formula C49H66N10O10S2 M. Wt 1019.24
  • Biological Activity
Description Octreotide is a synthetic somatostatin analogue that resembles the native polypeptide in its activity in suppressing levels and activity of growth hormone, insulin, glucagon and many other gastrointestinal peptides. Because its half-life is longer than somatostatin, octreotide can be used clinically to treat neuroendocrine tumors that secrete excessive amounts of growth hormone (acromegaly) or other active hormones or neuropeptides. Octreotide has many side effects including suppression of gall bladder contractility and bile production, and maintenance therapy can cause cholelithiasis, pancreatitis as well as clinically apparent liver injury.
Pathways GPCR/G Protein 
Targets Somatostatin Receptor 

Structure

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