TAK-659 hydrochloride
| CAS No. | 1952251-28-3 | Cat. No. | BCP28884 |
| Name | TAK-659 hydrochloride | ||
| Synonyms | TAK659 hydrochloride; TAK 659 hydrochloride; TAK-659 HCl; TAK659 HCl; TAK 659 HCl; | ||
| Formula | C17H22ClFN6O | M. Wt | 380.85 |
| Description | TAK-659 hydrochloride is an inhibitor of spleen tyrosine kinase (syk), with potential anti-inflammatory, immunomodulating, and antineoplastic activities. Spleen tyrosine kinase inhibitor TAK-659 may inhibit the activity of syk, which abrogates downstream B-cell receptor (BCR) signaling and leads to an inhibition of B-cell activation, chemotaxis, adhesion and proliferation. Note: TAK-659 free base is less stable. This product is supplied as dihydrochloride form. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | Syk | ||
Structure
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