GSK872

  • Chemical Properties
CAS No. 1346546-69-7 Cat. No. BCP28887
Name GSK872
Synonyms GSK 872; GSK-872; GSK 2399872A; GSK-2399872A; GSK2399872A;
Formula C19H17N3O2S2 M. Wt 383.49
  • Biological Activity
Description GSK872 (GSK2399872A) is a a receptor interacting protein kinase-3 (RIP3) inhibitor. GSK872 inhibits TNF- and virus-induced necrosis in 3T3-SA fibroblasts. It also inhibits necrosis induced by toll-like receptor 3 (TLR3).
Pathways Apoptosis Pathway 
Targets RIP 

Structure

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