MB 07133
CAS No. | 685111-92-6 | Cat. No. | BCP28904 |
Name | MB 07133 | ||
Synonyms | MB-07133; MB07133; | ||
Formula | C17H21N4O8P | M. Wt | 440.34 |
Description | MB07133 is a novel cytarabine (araC) prodrug that uses the HepDirect technology to target production of the active form of araC, araC triphosphate (araCTP), to the liver. As the levels of araCTP achieved in the liver at therapeutic doses are only toxic to proliferating cells (such as those in HCC tumors), but not the non-proliferative adjacent tissue, MB07133 treatment has the potential to be both efficacious and well tolerated in HCC patients. | ||
Pathways | Cell Cycle/DNA Damage | ||
Targets | DNA/RNA Synthesis |
Structure
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