YHO-13351
| CAS No. | 1346753-00-1 | Cat. No. | BCP28920 |
| Name | YHO-13351 | ||
| Synonyms | YHO13351;YHO 13351; | ||
| Formula | C27H37N3O7S2 | M. Wt | 579.73 |
| Description | YHO-13351 is an orally available prodrug of YHO-13177, which can specifically reverse BCRP/ABCG2-mediated drug resistance in vitro and in vivo; YHO-13351 is rapidly converted into YHO-13177 after its oral or intravenous administration, significantly increases the survival time of mice inoculated with BCRP-transduced murine leukemia P388 cells and suppressed the tumor growth in an HCT116/BCRP xenograft model coadministration of irinotecan. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | BCRP | ||
Structure
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