Cirsiliol
| CAS No. | 34334-69-5 | Cat. No. | BCP28925 |
| Name | Cirsiliol | ||
| Synonyms | 6-Hydroxyluteolin-6,7-dimethyl ether; 6-Methoxyluteolin 7-methyl ether; Crisiliol; | ||
| Formula | C17H14O7 | M. Wt | 330.29 |
| Description | Cirsiliol is a potent and selective 5-lipoxygenase inhibitor and a competitive low affinity benzodiazepine receptor ligand.Cirsiliol shows strong antioxidant activity. Cirsiliol can inhibit TG accumulation in 3T3-L1 preadipocytes, it may have anti-obesity effects. 3. Cirsiliol and rhamnetin can act as promising radiosensitizers that enhance the radiotherapeutic efficacy by inhibiting radiation-induced Notch-1 signaling associated with radioresistance possibly via miR-34a-mediated pathways. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Lipoxygenase | ||
Structure
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