ML221

  • Chemical Properties
CAS No. 877636-42-5 Cat. No. BCP28945
Name ML221
Synonyms ML 221; ML-221;
Formula C17H11N3O6S M. Wt 385.35
  • Biological Activity
Description ML221 is a potent apelin (APJ) functional antagonist, inhibiting apelin-13-mediated activation of APJ, with IC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, and EC80 of 10 nM in both assays.
Pathways Others Pathway 
Targets Others 

Structure

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