ML335

  • Chemical Properties
CAS No. 825658-06-8 Cat. No. BCP28963
Name ML335
Synonyms ML-335; ML 335; TREK-1/2 Activator;
Formula C15H14Cl2N2O3S M. Wt 373.25
  • Biological Activity
Description ML335 is a potent and selective TREK-1/2 Activator. ML335 is an agonist for OPRM1-OPRD1 heterdimerization with an EC50 of 403 nM, and selectivities vs. OPRM1, OPRD1, and HTR5A of 37, 2.7, and >99, respectively.
Pathways Ion Channel/Membrane Transporter 
Targets Potassium Channel 

Structure

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