IOX4

  • Chemical Properties
CAS No. 1154097-71-8 Cat. No. BCP29069
Name IOX4
Synonyms IOX-4; IOX 4;
Formula C15H16N6O3 M. Wt 328.33
  • Biological Activity
Description IOX4 is a potent inhibitor of PHD2 (IC50 = 1.6 nM). IOX4 induces HIFα in cells and in wildtype mice with marked induction in the brain tissue, revealing that it is useful for studies aimed at validating the upregulation of HIF for treatment of cerebral diseases including stroke.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets HIF 

Structure

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