VAS2870
| CAS No. | 722456-31-7 | Cat. No. | BCP29113 |
| Name | VAS2870 | ||
| Synonyms | VAS 2870;VAS-2870; | ||
| Formula | C18H12N6OS | M. Wt | 360.39 |
| Description | VAS2870 is a potent, specific NADPH oxidase (Nox) inhibitor; completely abolishes PDGF-mediated NAD(P)H oxidase activation and ROS production at 10-20 uM in vascular smooth muscle cells (VSMC); abrogates thalidomide stimulation of cardiomyogenesis; also impairs cell growth and enhances TGF-β-induced apoptosis of liver tumor cells. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | NOX | ||
Structure
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