Entasobulin
CAS No. | 501921-61-5 | Cat. No. | BCP29186 |
Name | Entasobulin | ||
Synonyms | |||
Formula | C26H18ClN3O2 | M. Wt | 439.89 |
Description | Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity. Entasobulin is a indolizine-glyoxylamide based small molecule that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes. The in vitro cytotoxic effects have been demonstrated across a wide array of tumor types of various origins (e.g., breast, colon, uterine). | ||
Pathways | Cell Cycle/DNA Damage | ||
Targets | Microtubule |
Structure
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