Entasobulin

  • Chemical Properties
CAS No. 501921-61-5 Cat. No. BCP29186
Name Entasobulin
Synonyms
Formula C26H18ClN3O2 M. Wt 439.89
  • Biological Activity
Description Entasobulin is a β-tubulin polymerization inhibitor with potential anticancer activity. Entasobulin is a indolizine-glyoxylamide based small molecule that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes. The in vitro cytotoxic effects have been demonstrated across a wide array of tumor types of various origins (e.g., breast, colon, uterine).
Pathways Cell Cycle/DNA Damage 
Targets Microtubule 

Structure

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