PE859
| CAS No. | 1402727-29-0 | Cat. No. | BCP29187 |
| Name | PE859 | ||
| Synonyms | PE-859;PE 859; | ||
| Formula | C28H24N4O2 | M. Wt | 448.52 |
| Description | PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66 and 1.2 μM, respectively. PE859 inhibits Amyloid-β and Tau Aggregation, and Ameliorates Cognitive Dysfunction in Senescence-Accelerated Mouse Prone 8. PE859 reduces aggregated tau and prevents onset and progression of neural dysfunction in vivo. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Microtubule | ||
Structure
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