Megestrol acetate
CAS No. | 595-33-5 | Cat. No. | BCP29265 |
Name | Megestrol acetate | ||
Synonyms | BDH 1298; BDH1298; BDH-1298; | ||
Formula | C24H32O4 | M. Wt | 384.51 |
Description | Megestrol acetate is the acetate ester of megestrol, a synthetic derivative of the naturally occurring female sex hormone progesterone, with progestogenic, antiestrogenic, and antineoplastic activities. Mimicking the action of progesterone, megestrol binds to and activates nuclear progesterone receptors (PRs) in the reproductive system and pituitary; ligand-receptor complexes are translocated to the nucleus where they bind to progesterone response elements (PREs) located on target genes. | ||
Pathways | Microbiology/Virology Hormone Pathay | ||
Targets | Progesterone Receptor HIV |
Structure
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