Megestrol acetate

  • Chemical Properties
CAS No. 595-33-5 Cat. No. BCP29265
Name Megestrol acetate
Synonyms BDH 1298; BDH1298; BDH-1298;
Formula C24H32O4 M. Wt 384.51
  • Biological Activity
Description Megestrol acetate is the acetate ester of megestrol, a synthetic derivative of the naturally occurring female sex hormone progesterone, with progestogenic, antiestrogenic, and antineoplastic activities. Mimicking the action of progesterone, megestrol binds to and activates nuclear progesterone receptors (PRs) in the reproductive system and pituitary; ligand-receptor complexes are translocated to the nucleus where they bind to progesterone response elements (PREs) located on target genes.
Pathways Microbiology/Virology Hormone Pathay 
Targets Progesterone Receptor HIV 

Structure

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