MIK 665
| CAS No. | 1799631-75-6 | Cat. No. | BCP29223 |
| Name | MIK 665 | ||
| Synonyms | MIK-665; MIK665; S 64315; S-64315; S64315; | ||
| Formula | C47H44ClFN6O6S | M. Wt | 875.41 |
| Description | MIK665, also known as S 64315, is an inhibitor of induced myeloid leukemia cell differentiation protein (Mcl-1; Bcl2-L-3), with potential pro-apoptotic and antineoplastic activities. Upon administration, MIK665 binds to and inhibits the activity of Mcl-1, which promotes apoptosis of cells overexpressing Mcl-1. Mcl-1, an anti-apoptotic protein belonging to the Bcl-2 family of proteins, is upregulated in cancer cells and promotes tumor cell survival | ||
| Related Products | 1799831-02-9（(R)-MIK665） | ||
| Pathways | Apoptosis Pathway | ||
| Targets | Bcl2 | ||
Structure
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