Uridine Diphosphate Glucuronic Acid
| CAS No. | 2616-64-0 | Cat. No. | BCP29224 |
| Name | Uridine Diphosphate Glucuronic Acid | ||
| Synonyms | Uridine Diphosphoglucuronic Acid;Glucuronic Acid, UDP;UDP Glucuronic Acid;UDPGA;UDP-a-D-galacturonic acid;Uridine diphosphate;UDP-glucuronic acid;Uridine 5-diphosphoglucuronic acid; UDPglucuronate; | ||
| Formula | C15H22N2O18P2 | M. Wt | 580.29 |
| Description | Uridine diphosphate glucuronic acid is a nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP Iduronic acid, which donates Iduronic acid to polysaccharides. In animals, UDP glucuronic acid is used for formation of many glucosiduronides with various aglycones. The transfer of glucuronic acid from UDP-alpha-D-glucuronic acid onto a terminal galactose residue is done by beta1, 3-glucuronosyltransferases, responsible for the completion of the protein-glycosaminoglycan linkage region of proteoglycans and of the HNK1 epitope of glycoproteins and glycolipids. In humans the enzyme galactose-beta-1, 3-glucuronosyltransferase I completes the synthesis of the common linker region of glycosaminoglycans (GAGs) by transferring glucuronic acid (GlcA) onto the terminal galactose of the glycopeptide primer of proteoglycans. The GAG chains of proteoglycans regulate major biological processes such as cell proliferation and recognition, extracellular matrix deposition, and morphogenesis. |
Structure
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