NAV-2729
| CAS No. | 419547-11-8 | Cat. No. | BCP29254 |
| Name | NAV-2729 | ||
| Synonyms | NAV 2729; NAV2729; | ||
| Formula | C25H17ClN4O3 | M. Wt | 456.88 |
| Description | NAV-2729 is a selective ARF6 inhibitor (IC50 = 1.0 μM). Blocking ARF6 with a small-molecule inhibitor reduces uveal melanoma cell proliferation and tumorigenesis in a mouse model, confirming the functional relevance of this pathway and suggesting a therapeutic strategy for Gα-mediated diseases. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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