PA 6
CAS No. | 500715-03-7 | Cat. No. | BCP29257 |
Name | PA 6 | ||
Synonyms | PA6;Pentamidine-Analogue 6;IK1 inhibitor PA-6;1,5-Bis[4-[[imino(phenyl)methyl]amino]phenoxy]pentane; | ||
Formula | C31H32N4O2 | M. Wt | 492.61 |
Description | PA-6 is a selective and potent IK1 (inward rectifier potassium current) inhibitor that terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models. PA-6 interacts with the cytoplasmic pore region of the KIR2.1 (KCNJ2) ion channel. | ||
Pathways | Ion Channel/Membrane Transporter | ||
Targets | Potassium Channel |
Structure
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