Shikonin
| CAS No. | 517-89-5 | Cat. No. | BCP29329 |
| Name | Shikonin | ||
| Synonyms | (-)-Shikonin;C.I. 75535; Isoarnebin 4; | ||
| Formula | C16H16O5 | M. Wt | 288.3 |
| Description | Shikonin is a natural product from the root of Lithospermum erythrorhizon and a specific inhibitor of pyruvate kinase M2 (PKM2). Shikonin also suppresses the ATF2 pathway in skin carcinogenesis. | ||
| Pathways | Ion Channel/Membrane Transporter Protease/Metabolic Enzyme Apoptosis Pathway NFκB | ||
| Targets | Chloride Channel Pyruvate Kinase TNF Receptor NF κB | ||
Structure
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