碘苷
| CAS号 | 54-42-2 | 货号 | BCP29428 |
| 中文名 | 碘苷 | ||
| 英文名 | (+)-5-Iodo-2'-deoxyuridine | ||
| 中文别名 | 5-碘-2 -脱氧尿苷; | ||
| 英文别名 | 5-IUdR; IDU; IdUrd; Idoxuridine; | ||
| 分子式 | C9H11IN2O5 | 分子量 | 354.1 |
| 生物活性 | Idoxuridine is an anti-herpesvirus antiviral and anticancer drug. It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. It is used only topically due to cardiotoxicity. It was synthesized by William Prusoff in the late 1950s. Initially developed as an anticancer drug, idoxuridine became the first antiviral agent in 1962. | ||
| 信号通路 | Microbiology/Virology | ||
| 靶 点 | HSV | ||
结构式
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