Piritrexim

  • Chemical Properties
CAS No. 72732-56-0 Cat. No. BCP29680
Name Piritrexim
Synonyms BW 301U;BW301U;
Formula C17H19N5O2 M. Wt 325.37
  • Biological Activity
Description Piritrexim is a synthetic antifolate agent with antiparasitic, antipsoriatic and antitumor properties. Piritrexim inhibits the enzyme dihydrofolate reductase enzyme, thereby disrupting folate metabolism and DNA synthesis and cell division.
Pathways Cell Cycle/DNA Damage 
Targets DHFR 

Structure

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