GDC-0575 dihydrochloride

  • Chemical Properties
CAS No. 1657014-42-0 Cat. No. BCP29768
Name GDC-0575 dihydrochloride
Synonyms GDC0575 dihydrochloride;GDC 0575 dihydrochloride;ARRY-575 dihydrochloride; RG7741 dihydrochloride;ARRY 575 dihydrochloride; RG 7741 dihydrochloride;ARRY575 dihydrochloride; RG 7741 dihydrochloride;
Formula C16H22BrCl2N5O M. Wt 451.19
  • Biological Activity
Description GDC-0575 dihydrochloride is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity.
Pathways Cell Cycle/DNA Damage 
Targets Checkpoint 

Structure

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