GDC-0575 dihydrochloride
CAS No. | 1657014-42-0 | Cat. No. | BCP29768 |
Name | GDC-0575 dihydrochloride | ||
Synonyms | GDC0575 dihydrochloride;GDC 0575 dihydrochloride;ARRY-575 dihydrochloride; RG7741 dihydrochloride;ARRY 575 dihydrochloride; RG 7741 dihydrochloride;ARRY575 dihydrochloride; RG 7741 dihydrochloride; | ||
Formula | C16H22BrCl2N5O | M. Wt | 451.19 |
Description | GDC-0575 dihydrochloride is an orally bioavailable CHK1 inhibitor, with an IC50 of 1.2 nM, and has antitumor activity. | ||
Pathways | Cell Cycle/DNA Damage | ||
Targets | Checkpoint |
Structure
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