CP-105696

  • Chemical Properties
CAS No. 158081-99-3 Cat. No. BCP30009
Name CP-105696
Synonyms Pfizer 105696;CP105696; CP-105696; CP 105,696;CP-105,696;CP105,696;
Formula C28H28O4 M. Wt 428.52
  • Biological Activity
Description CP 105696 is a potent and selective leukotriene B4(LTB4) receptor antagonist. In vitro, CP-105696 inhibited LTB4 (0.3 nM) binding to high-affinity LTB4 receptors on human neutrophils with an IC50 value of 8.42 +/- 0.26 nM. The therapeutic potential of CP-105696, an BLT1 inhibitor, prevents and treats arthritis.
Pathways GPCR/G Protein 
Targets Leukotriene Receptor 

Structure

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