TM-5441
| CAS No. | 1190221-43-2 | Cat. No. | BCP30131 |
| Name | TM-5441 | ||
| Synonyms | TM5441; BMS-790052; BMS-790052; BMS790052; EBP 883; EBP-883; EBP883; | ||
| Formula | C21H17ClN2O6 | M. Wt | 428.82 |
| Description | TM-5441, also known as EBP 883 and BMS-790052, is a potent plasminogen activator inhibitor-1 (PAI-1). TM-5441 inhibits several tumor cell lines with IC50 values between 9.7 and 60.3 μM. TM5441 protects against high-fat diet-induced obesity and adipocyte injury in mice. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | PAI1 | ||
Structure
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