ODM-203 HCl
| CAS号 | ODM-203hcl | 货号 | BCP30289 |
| 中文名 | ODM-203 HCl | ||
| 英文名 | ODM-203 HCl | ||
| 中文别名 | |||
| 英文别名 | ODM 203 HCl;ODM203 HCl;ODM-203 hydrochloride;ODM203 hydrochloride; | ||
| 分子式 | C26H22ClF2N5O2S | 分子量 | 542.00 |
| 生物活性 | ODM-203 is an orally available inhibitor of the human vascular endothelial growth factor receptors (VEGFRs) and fibroblast growth factor receptors (FGFRs), with potential antiangiogenic and antineoplastic activities. VEGFR/FGFR inhibitor ODM-203 inhibits both VEGFRs and FGFRs, which may result in the inhibition of VEGFR- and FGFR-mediated signaling. This leads to an inhibition of angiogenesis and cell proliferation in tumor cells overexpressing VEGFR and/or FGFR. Both VEGFRs and FGFRs belong to the superfamily of receptor tyrosine kinases and are upregulated in various tumor cell types. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | VEGFR FGFR | ||
结构式
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