BMX-IN-1
| CAS号 | 1431525-23-3 | 货号 | BCP30306 |
| 中文名 | BMX-IN-1 | ||
| 英文名 | BMX-IN-1 | ||
| 中文别名 | |||
| 英文别名 | BMX-IN1; BMX-IN 1;BMX kinase inhibitor; | ||
| 分子式 | C29H24N4O4S | 分子量 | 524.59 |
| 生物活性 | BMX-IN-1 is a selective irreversible BMX inhibitor for prostate cancer. BMX-IN-1 can covalently modifies Cys496. BMX-IN-1 inhibits the proliferation of Tel-BMX-transformed Ba/F3 cells at two digit nanomolar concentrations but requires single digit micromolar concentrations to inhibit the proliferation of prostate cancer cell lines. MK2206, is able to potentiate BMX inhibitor's antiproliferation efficacy against prostate cancer cells. | ||
| 信号通路 | Angiogenesis/Protein Tyrosine Kinase | ||
| 靶 点 | BTK | ||
结构式
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