BLU-782

  • Chemical Properties
CAS No. 2141955-96-4 Cat. No. BCP30344
Name BLU-782
Synonyms BLU782;BLU 782;
Formula C31H42N6O4 M. Wt 562.71
  • Biological Activity
Description BLU-782 (BLU782) is a novel potent, selective inhibitor of Activin receptor-like kinase (ALK2) mutant R206H with binding IC50 of <10 nM; BLU-782 is a development candidate for the treatment of fibrodysplasia ossificans progressiva, example 876 in patent WO 2017181117 A1.
Pathways TGF beta/Smad  
Targets TGF β/Smad 

Structure

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