LXS-196 2HCl
| CAS号 | LXS-196HCl | 货号 | BCP30427 |
| 中文名 | LXS-196 2HCl | ||
| 英文名 | LXS-196 2HCl | ||
| 中文别名 | |||
| 英文别名 | NVP-LXS196; NVPLXS196; NVP LXS196; LXS196; LXS-196; LXS 196; | ||
| 分子式 | C22H25Cl2F3N8O | 分子量 | 544.15 |
| 生物活性 | LXS-196 is a potent and orally active protein kinase C inhibitor for the treatment of uveal melanoma. Upon oral administration, protein kinase C inhibitor LXS196 binds to and inhibits PKC, which prevents the activation of PKC-mediated signaling pathways. This may lead to the induction of cell cycle arrest and apoptosis in susceptible tumor cells. PKC, a serine/threonine protein kinase overexpressed in certain types of cancer cells, is involved in tumor cell differentiation, proliferation, invasion and survival. | ||
| 信号通路 | TGF beta/Smad Epigenetics | ||
| 靶 点 | PKC | ||
结构式
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