MK-0731

  • Chemical Properties
CAS No. 845256-65-7 Cat. No. BCP30541
Name MK-0731
Synonyms MK0731; MK 0731;ALR-3456;ALR3456;ALR 3456;
Formula C25H28F3N3O2 M. Wt 459.51
  • Biological Activity
Description MK-0731 is a synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP.
Pathways Cell Cycle/DNA Damage 
Targets Kinesin 

Structure

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