eFT508 HCl
| CAS No. | 1849590-02-8 | Cat. No. | BCP30543 |
| Name | eFT508 HCl | ||
| Synonyms | Tomivosertib HCl;Tomivosertib hydrochloride;eFT 508 HCl;eFT-508 HCl ; eFT508 hydrochloride; eFT-508 hydrochloride; eFT 508 hydrochloride; | ||
| Formula | C17H21ClN6O2 | M. Wt | 376.84 |
| Description | eFT508 is a MNK1/2 inhibitor. Tomivosertib binds to and inhibits the activity of MNK1 and 2. This prevents MNK1/2-mediated signaling, and inhibits the phosphorylation of certain regulatory proteins, including eukaryotic translation initiation factor 4E (eIF4E), that regulate the translation of messenger RNAs (mRNAs) involved in tumor cell proliferation, angiogenesis, survival and immune signaling. | ||
| Pathways | MAPK Pathway | ||
| Targets | MNK | ||
Structure
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