NCC007
| CAS No. | 2342583-66-6 | Cat. No. | BCP30832 |
| Name | NCC007 | ||
| Synonyms | NCC-007; NCC 007; | ||
| Formula | C22H28F3N7 | M. Wt | 447.51 |
| Description | NCC007 is a novel CKIα and CKIδ dual inhibitor. NCC007 that showed stronger period effects (0.32 μM for 5 h period lengthening) in a cellbased circadian assay. The following in vitro kinase assay showed that NCC007 inhibited CKIα and CKIδ with an IC50 of 1.8 and 3.6 μM. We further demonstrated that NCC007 lengthened the period of mouse behavioral rhythms in vivo. Thus, NCC007 is a valuable tool compound to control circadian rhythms through CKI inhibition. | ||
| Pathways | Cell Cycle/DNA Damage Wnt/Stem Cell | ||
| Targets | Casein Kinase | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.