FT113
| CAS No. | 1630808-89-7 | Cat. No. | BCP31017 |
| Name | FT113 | ||
| Synonyms | FT-113;FT 113; | ||
| Formula | C22H20FN3O4 | M. Wt | 409.4 |
| Description | FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC50, 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer both in vitro and in vivo. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | FAS | ||
Structure
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