KL1333

  • Chemical Properties
CAS No. 1800405-30-4 Cat. No. BCP31080
Name KL1333
Synonyms KL 1333;KL-1333;
Formula C14H12N2O2 M. Wt 240.26
  • Biological Activity
Description KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation.KL1333 induced the activation of SIRT1, AMPK, and PGC-1α. In addition, KL1333 increased energy production and mitochondrial function and decreased oxidative stress in MELAS fibroblasts.
Pathways Others Pathway 
Targets Others 

Structure

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