非唑奈坦

  • 化学数据
CAS号 1629229-37-3 货号 BCP31288
中文名 非唑奈坦
英文名 Fezolinetant
中文别名
英文别名 ESN-364; ESN 364; ESN364;
分子式 C16H15FN6OS 分子量 358.39
  • 用途
生物活性 Fezolinetant, also known as ESN-364, is Neurokinin-3 (NK-3) receptor antagonist which has been optimized for use in women’s health, and is being developed for sex-hormone related disorders such as endometriosis, polycystic ovarian syndrome and uterine fibroids. Fexolinetant allows modulation of the hypothalamic-pituitary gonadal axis with a selective action on hormones relevant to disease. The agent is expected to have greater tolerability than competing products which target GnRH (Gonadotropin-releasing hormone).
信号通路 Neuro Signaling Pathway GPCR/G Protein 
靶 点 NK Receptor 

结构式

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